Radial Cath Kits Recalled; siRNAs for Lipid Lowering; Smartphone HF Detection | MedPage Today

Oct 14, 2024

by Nicole Lou, Senior Staff Writer, MedPage Today April 9, 2024

Gamification of daily step goals and financial incentives resulted in increased physical activity over 1 year. (Circulation)

Ambulatory heart rate varies widely between healthy middle-aged individuals and cannot be predicted by typical clinical variables. (Heart)

In the DEDICATE-DZHK6 population, designed to be more reflective of routine clinical practice, transcatheter aortic valve replacement matched surgery for outcomes at 1 year among people at low or intermediate surgical risk. (New England Journal of Medicine)

Arrow QuickFlash radial artery and radial artery/arterial line catheterization kits are under class I recall due to reports of increased resistance in the guidewire handle and chamber during use, the FDA announced.

Around 10% of all deaths following percutaneous coronary intervention could have been avoided, according to research highlighted by the University of Michigan.

Coronary artery bypass grafting surgery may be feasibly planned without invasive coronary angiography. (European Heart Journal)

Investigational APOC3-targeting small interfering RNA (siRNA) therapy plozasiran reduced serum triglycerides in patients with severe hypertriglyceridemia in a phase IIb study. (JAMA Cardiology)

Early data support zerlasiran as a siRNA for reducing lipoprotein(a) concentrations in people with stable heart disease. (JAMA)

Esperion pointed to the consistent clinical benefits of bempedoic acid (Nexletol) across sex, race, and diabetes status in the CLEAR Outcomes trial.

With mechanical thrombectomy in stroke patients without salvageable tissue identified on CT perfusion imaging, recanalization was still linked to better functional outcomes, a retrospective study showed. (Stroke)

People with diabetic cardiomyopathy did not show improved exercise capacity after taking the highly selective aldose reductase inhibitor AT-001. (Journal of the American College of Cardiology)

Smartphone motion sensors allowed CardioSignal algorithms to accurately detect stage C heart failure in a multicenter prospective study. (JACC: Heart Failure)

For rural Native Americans with limited access to care, a phone-based telehealth service for heart failure with reduced ejection fraction boosted uptake of guideline-directed medical therapy. (JAMA Internal Medicine)

Older people with heart failure who displayed bendopnea, the shortness of breath after bending over, had disproportionately higher mortality rates. (European Journal of Preventive Cardiology)

The existing bone drug etidronate slowed the progression of arterial calcification due to deficiency of CD73, a rare disease. (Vascular Medicine)

Like other racial groups, Asian Americans show a link between social determinants of health and cardiovascular disease risk factors. (Journal of the American Heart Association)

Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine. Follow